Chymotrypsin-C


Chymotrypsin-C
Chymotrypsin C (caldecrin)
Identifiers
Symbols CTRC; CLCR; ELA4
External IDs OMIM601405 MGI1923951 HomoloGene21422 GeneCards: CTRC Gene
EC number 3.4.21.2
Orthologs
Species Human Mouse
Entrez 11330 76701
Ensembl ENSG00000162438 ENSMUSG00000062478
UniProt Q99895 Q3SYP2
RefSeq (mRNA) NM_007272 NM_001033875.2
RefSeq (protein) NP_009203 NP_001029047.1
Location (UCSC) Chr 1:
15.76 – 15.78 Mb
Chr 4:
141.39 – 141.4 Mb
PubMed search [1] [2]

Chymotrypsin C, also known as caldecrin or elastase 4 is an enzyme that in humans is encoded by the CTRC gene.[1][2]

Function

Chymotrypsin C is a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity.[1]

References

  1. ^ a b "Entrez Gene: chymotrypsin C (caldecrin)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11330. 
  2. ^ Tomomura A, Akiyama M, Itoh H, Yoshino I, Tomomura M, Nishii Y, Noikura T, Saheki T (May 1996). "Molecular cloning and expression of human caldecrin". FEBS Lett. 386 (1): 26–8. doi:10.1016/0014-5793(96)00377-8. PMID 8635596. 

Further reading


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Chymotrypsin — Crystallographic structure of Bos taurus chymotrypsinogen.[1] Identifiers EC number …   Wikipedia

  • Chymotrypsin B — Bändermodell von Chymotrypsin nach PDB  …   Deutsch Wikipedia

  • Chymotrypsin — B Größe 241 = 13+131+97 AA Precursor Chymotrypsinogen B (245 AA) Bezeich …   Deutsch Wikipedia

  • Chymotrypsin — Chymotrypsin, zu den Endopeptidasen (⇒ Proteasen) gehörendes, Proteine zu Oligopeptiden spaltendes Verdauungsenzym der Wirbeltiere, das sein pH Optimum im alkalischen Bereich (pH 7–8) hat und bevorzugt Peptidbindungen spaltet, deren… …   Deutsch wörterbuch der biologie

  • chymotrypsin — [kī΄mō trip′sin] n. [< Gr chymos (see CHYME) + TRYPSIN] a pancreatic enzyme that is important in the digestion of proteins in the intestines …   English World dictionary

  • Chymotrypsin — Chy|mo|tryp|sin [↑ Chymo u. ↑ Trypsin], das; s, e: in der Bauchspeicheldrüse aus Vorstufen (Chymotrypsinogenen) gebildete Verdauungsenzyme (↑ Proteinasen), die auch med. Verwendung in der Wundheilung u. Ödemtherapie finden. * * * Chymotrypsin  … …   Universal-Lexikon

  • chymotrypsin — C. A or B; a serine proteinase of the gastrointestinal tract that preferentially cleaves carboxyl links of hydrophobic amino acid s, particularly at tyrosyl, tryptophanyl, phenylalanyl, and leucyl residues; synthesized in the pancreas as… …   Medical dictionary

  • chymotrypsin — n. a protein digesting enzyme (see peptidase). It is secreted by the pancreas in an inactive form, chymotrypsinogen, that is converted into chymotrypsin in the duodenum by the action of trypsin …   The new mediacal dictionary

  • chymotrypsin — chimotripsinas statusas T sritis chemija apibrėžtis Proteazė, skaidanti Phe, Tyr, Trp karboksigrupių sudarytus peptidinius ryšius. atitikmenys: angl. chymotrypsin rus. химотрипсин …   Chemijos terminų aiškinamasis žodynas

  • chymotrypsin — noun Etymology: chyme + o + trypsin Date: 1933 a protease that hydrolyzes peptide bonds and is formed in the intestine from chymotrypsinogen • chymotryptic adjective …   New Collegiate Dictionary


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.